Publications
BRADY LAB
Jarvis AF, Bhat MY, Maujean T, Abreu AL, Toy K, Burslem GM, Brady DC.ACS Bio Med Chem Au. 2026 Jan 23;6(2):178-191. doi: 10.1021/acsbiomedchemau.5c00231. eCollection 2026 Apr 15.PMID: 42006249 Free PMC article.
BURSLEM LAB
General Strategy for Controlling Functional Lysine Acetylation via Induced Proximity.
Hill-Payne B, Bhat MY, Burslem GM. ACS Chem Biol. 2026 Aug 24. doi: 10.1021/acschembio.6c00510. Online ahead of print. PMID: 42671073
Quinazolinone and Phthalazinone Inhibitors of the HDAC6/Ubiquitin Protein-Protein Interaction.
Gordon S, Hintzen JCJ, Dilones S, Keen B, Crawford CEW, Burslem GM. Chembiochem. 2026 Jun 26;27(12):e70423. doi: 10.1002/cbic.70423.
BUSINO LAB
Combinatorial use of VHL and KEAP1 PROTACs reveals unexpected synergy and hook effect relief.
Islam S, Jin H, Liu D, Lu D, Zhang Y, Christenson E, Chang R, Austin J, Faustino A, Beer T, Tang HY, Huang L, Tonra JR, Busino L.Genes Dev. 2026 Mar 2;40(5-6):308-318. doi: 10.1101/gad.352916.125.PMID: 41360670
CHODOSH LAB
Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy.
Sreekumar A, Blankemeyer E, Sterner CJ, Pan TC, Pant DK, Acolatse S, Turkistani H, Belka GK, Nayak A, Carlin SD, Assenmacher CA, Sellmyer MA, Mankoff DA, Chodosh LA.Cancer Discov. 2026 Apr 1;16(4):781-799. doi: 10.1158/2159-8290.CD-25-0919.PMID: 41370830 Free PMC article.
FELDSER LAB
Tumor suppressor genotype influences the extent and mode of immunosurveillance in lung cancer.
Adler KM, Xu H, Gladstein AC, Irizarry-Negron VM, Robertson MR, Doerig KR, Petrov DA, Winslow MM, Feldser DM. Nat Commun. 2026 Jun 15. doi: 10.1038/s41467-026-74023-x. Online ahead of print. PMID: 42297823
GADE LAB
PSIP1::TBL1X: a recurrent gene fusion in pancreatic neuroendocrine tumors.
Ackerman D, Seyferth ER, Li W, Youngman JE, Cottone JN, Wright CA, Sussman RT, Woodard AA, Metz DC, Katona BW, Soulen MC, DePietro DM, Eads JR, Gade TP. Endocr Relat Cancer. 2026 Aug 27:ERC-26-0177. doi: 10.1530/ERC-26-0177. Online ahead of print. PMID: 42659417
Boehmler DJ, Baron RJ, Brain JA, Islam A, Kim Y, Gurevich A, Perkons NR, Zavriyev AI, Amin R, Andrew-Udoh J, Tuzneen Supan E, El Ghazal R, Hunt SJ, McClung G, Tischfield D, Ackerman D, Weljie AM, Weinfurtner K, Skuli N, Gade TPF.Hepatology. 2026 Apr 30. doi: 10.1097/HEP.0000000000001775. Online ahead of print.PMID: 42059877
GREENBERG LAB
Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex
Foglizzo M, Datta A, Degtjarik O, Perera H, Liburd J, Sykora UM, Ganji SR, Wildsmith G, Chandler F. Campbell LJ, Calabrese AN, Greenberg RA*, Zeqiraj E*. Nat Commun. 2026 Aug 11;17(1):8091. doi:10.1038/s41467-026-75795-y.
The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells
Datta A, Jackson J, Morozov YI, Qiu J, Vindigni A, Greenberg RA. Nat Commun. 2026 Jul 4. doi:10.1038/s41467-026-75271-7. Online ahead of print.
HUANG LAB
Antigen-specific profiling identifies T-bet+ melanoma-specific CD8+ T cells associated with response to neoadjuvant PD-1 blockade.
Wang G, Yoon D, Nandi A, Patel K, Azar T, Kim J, Han NA, Nickie A, Park S, Wang K, Yan P, Divaker S, Tabita-Martinez J, Giles L, Carberry M, Beltra JC, Painter MM, Alanio C, Amaravadi RK, Schuchter LM, Carreno BM, Linette GP, Elder DE, Brody RM, Gimotty P, Miura JT, Karakousis GC, Xu X, Mitchell TC, Huang AC.Cancer Cell. 2026 Jan 12;44(1):221-234.e5. doi: 10.1016/j.ccell.2025.12.004. Epub 2025 Dec 31.PMID: 41478278 Clinical Trial.
JIN LAB
Tumour-brain crosstalk restrains cancer immunity via a sensory-sympathetic axis.
Wei HK, Yu CD, Hu B, Zeng X, Ichise H, Li L, Wang Y, Wang RL, Germain RN, Chang RB, Jin C.Nature. 2026 Feb;650(8103):1007-1016. doi: 10.1038/s41586-025-10028-8. Epub 2026 Feb 4.PMID: 41639447 Free PMC article.
SHI LAB
Inducible, split base editors for in vivo cancer functional genomics.
Ren D, Wang S, Yamada K, Liu Y, Hapke R, Alpsoy A, Ho Y, Zhang C, Lan Y, Zhang S, Milazzo JP, Lohia R, Berríos KN, Li Y, Weber EW, Li Q, Vakoc CR, Minn AJ, Kohli RM, Shi J.Nat Biotechnol. 2026 Apr 15. doi: 10.1038/s41587-026-03077-5. Online ahead of print.PMID: 41986696
Cao Z, Yu S, Peng J, Barrett DR, Liu Y, Sussman JH, Chen C, Thadi A, Liu L, Alikarami F, Xu J, Carroll MP, Tan K, Bernt KM, Shi J.Mol Cell. 2026 Mar 5;86(5):968-985.e7. doi: 10.1016/j.molcel.2026.02.003. Epub 2026 Feb 26.PMID: 41759529 Free PMC article.
SILVERBUSH LAB
The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM.
Freeburg NF, Chafamo D, Konanur Gopikrishna G, Murphy RM, Peng JJ, Parthasarathy S, Dumont S, Estrada EG, Logun MT, Sun Y, Wang X, Grover P, Rodriguez JL, Zhang DL, Park K, Fu Y, Ben Hamouda N, Hernandez-Verdin I, Lamrani L, Hicks KA, Cooper NA, Ekwegbara C, Bawden EG, Waterfall JJ, Fuentealba J, Alcantara M, Seykora JT, Prouty SM, Barrett D, Banerjee E, Cox A, Assenmacher CA, Macia C, Yin M, Carpenter EL, Ming GL, Sautès-Fridman C, Fridman WH, Tartour E, Wherry EJ, Amigorena S, Fraietta JA, Nasrallah MP, Song H, Miller TE, Bagley SJ, O'Rourke DM, Binder ZA, Alanio C, Silverbush D. Cell. 2026 Jun 15:S0092-8674(26)00585-4. doi: 10.1016/j.cell.2026.05.026. Online ahead of print.PMID: 42296961
WAN LAB
RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription.
Budinich KA, Yao X, Gong C, Song L, Wang X, Lee MC, Mathias KM, Li Q, Tang S, Liu Y, Nguyen SC, Joyce EF, Li Y, Li H, Wan L.Mol Cell. 2026 Jun 12:S1097-2765(26)00348-5. doi: 10.1016/j.molcel.2026.05.024. Online ahead of print.PMID: 42285105
WELLEN LAB
Acetyl-CoA-dependent processes are preferentially supported by local metabolite synthesis.
Supplee JG, Costa-Pinheiro P, Wessendorf-Rodriguez K, Stransky S, Yang Q, Demetriadou C, Murali N, Li J, Pennise JL, Marcinkiewicz MM, Sidoli S, Snyder NW, Metallo CM, Marmorstein R, Wellen KE. Sci Adv. 2026 Sep 11;12(37):eaee4935. doi: 10.1126/sciadv.aee4935. Epub 2026 Sep 11. PMID: 42726866