Publications

Wan lab

RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription.

Budinich KA, Yao X, Gong C, Song L, Wang X, Lee MC, Mathias KM, Li Q, Tang S, Liu Y, Nguyen SC, Joyce EF, Li Y, Li H, Wan L.Mol Cell. 2026 Jun 12:S1097-2765(26)00348-5. doi: 10.1016/j.molcel.2026.05.024. Online ahead of print.PMID: 42285105

Gade lab

Locoregional lactate dehydrogenase inhibition potentiates therapy and overcomes treatment resistance in hepatocellular carcinoma.

Boehmler DJ, Baron RJ, Brain JA, Islam A, Kim Y, Gurevich A, Perkons NR, Zavriyev AI, Amin R, Andrew-Udoh J, Tuzneen Supan E, El Ghazal R, Hunt SJ, McClung G, Tischfield D, Ackerman D, Weljie AM, Weinfurtner K, Skuli N, Gade TPF.Hepatology. 2026 Apr 30. doi: 10.1097/HEP.0000000000001775. Online ahead of print.PMID: 42059877

Brady and Burslem labs

MAPK Pathway Inhibition Reshapes Kinase Chemical Probe Reactivity Reflecting Cellular Activation States.

Jarvis AF, Bhat MY, Maujean T, Abreu AL, Toy K, Burslem GM, Brady DC.ACS Bio Med Chem Au. 2026 Jan 23;6(2):178-191. doi: 10.1021/acsbiomedchemau.5c00231. eCollection 2026 Apr 15.PMID: 42006249 Free PMC article.

Shi lab

Inducible, split base editors for in vivo cancer functional genomics.

Ren D, Wang S, Yamada K, Liu Y, Hapke R, Alpsoy A, Ho Y, Zhang C, Lan Y, Zhang S, Milazzo JP, Lohia R, Berríos KN, Li Y, Weber EW, Li Q, Vakoc CR, Minn AJ, Kohli RM, Shi J.Nat Biotechnol. 2026 Apr 15. doi: 10.1038/s41587-026-03077-5. Online ahead of print.PMID: 41986696

Shi lab

CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples.

Cao Z, Yu S, Peng J, Barrett DR, Liu Y, Sussman JH, Chen C, Thadi A, Liu L, Alikarami F, Xu J, Carroll MP, Tan K, Bernt KM, Shi J.Mol Cell. 2026 Mar 5;86(5):968-985.e7. doi: 10.1016/j.molcel.2026.02.003. Epub 2026 Feb 26.PMID: 41759529 Free PMC article.

Jin lab

Tumour-brain crosstalk restrains cancer immunity via a sensory-sympathetic axis.

Wei HK, Yu CD, Hu B, Zeng X, Ichise H, Li L, Wang Y, Wang RL, Germain RN, Chang RB, Jin C.Nature. 2026 Feb;650(8103):1007-1016. doi: 10.1038/s41586-025-10028-8. Epub 2026 Feb 4.PMID: 41639447 Free PMC article.

Huang lab

Antigen-specific profiling identifies T-bet⁺ melanoma-specific CD8⁺ T cells associated with response to neoadjuvant PD-1 blockade.

Wang G, Yoon D, Nandi A, Patel K, Azar T, Kim J, Han NA, Nickie A, Park S, Wang K, Yan P, Divaker S, Tabita-Martinez J, Giles L, Carberry M, Beltra JC, Painter MM, Alanio C, Amaravadi RK, Schuchter LM, Carreno BM, Linette GP, Elder DE, Brody RM, Gimotty P, Miura JT, Karakousis GC, Xu X, Mitchell TC, Huang AC.Cancer Cell. 2026 Jan 12;44(1):221-234.e5. doi: 10.1016/j.ccell.2025.12.004. Epub 2025 Dec 31.PMID: 41478278 Clinical Trial.

Chodosh lab

Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy.

Sreekumar A, Blankemeyer E, Sterner CJ, Pan TC, Pant DK, Acolatse S, Turkistani H, Belka GK, Nayak A, Carlin SD, Assenmacher CA, Sellmyer MA, Mankoff DA, Chodosh LA.Cancer Discov. 2026 Apr 1;16(4):781-799. doi: 10.1158/2159-8290.CD-25-0919.PMID: 41370830 Free PMC article.

Busino lab

Combinatorial use of VHL and KEAP1 PROTACs reveals unexpected synergy and hook effect relief.

Islam S, Jin H, Liu D, Lu D, Zhang Y, Christenson E, Chang R, Austin J, Faustino A, Beer T, Tang HY, Huang L, Tonra JR, Busino L.Genes Dev. 2026 Mar 2;40(5-6):308-318. doi: 10.1101/gad.352916.125.PMID: 41360670

Feldser lab

Tumor suppressor genotype influences the extent and mode of immunosurveillance in lung cancer. 

Adler KM, Xu H, Gladstein AC, Irizarry-Negron VM, Robertson MR, Doerig KR, Petrov DA, Winslow MM, Feldser DM. Nat Commun. 2026 Jun 15. doi: 10.1038/s41467-026-74023-x. Online ahead of print.

PMID: 42297823    

 Burslem lab

Quinazolinone and Phthalazinone Inhibitors of the HDAC6/Ubiquitin Protein-Protein Interaction.

Gordon S, Hintzen JCJ, Dilones S, Keen B, Crawford CEW, Burslem GM. Chembiochem. 2026 Jun 26;27(12):e70423. doi: 10.1002/cbic.70423.

Silverbush lab

The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM.

Freeburg NF, Chafamo D, Konanur Gopikrishna G, Murphy RM, Peng JJ, Parthasarathy S, Dumont S, Estrada EG, Logun MT, Sun Y, Wang X, Grover P, Rodriguez JL, Zhang DL, Park K, Fu Y, Ben Hamouda N, Hernandez-Verdin I, Lamrani L, Hicks KA, Cooper NA, Ekwegbara C, Bawden EG, Waterfall JJ, Fuentealba J, Alcantara M, Seykora JT, Prouty SM, Barrett D, Banerjee E, Cox A, Assenmacher CA, Macia C, Yin M, Carpenter EL, Ming GL, Sautès-Fridman C, Fridman WH, Tartour E, Wherry EJ, Amigorena S, Fraietta JA, Nasrallah MP, Song H, Miller TE, Bagley SJ, O'Rourke DM, Binder ZA, Alanio C, Silverbush D. Cell. 2026 Jun 15:S0092-8674(26)00585-4. doi: 10.1016/j.cell.2026.05.026. Online ahead of print.PMID: 42296961