Research Highlights

Silverbush Lab: Immune activation may determine success of dual-target CAR T therapy in glioblastoma

Activation of natural killer cells are linked to longer survival, and suppressive immune cells are tied to poor response, Penn research finds.

Shi Lab: First CRISPR-based platform to pinpoint leukemia drivers

The new toolkit, developed by Penn Medicine and Children’s Hospital of Philadelphia, allows researchers to test potential cancer targets directly in patient leukemia cells.

Chodosh Lab: Pioneering strategy may keep breast cancer from coming back 

A clinical trial led by scientists from the Abramson Cancer Center and the Perelman School of Medicine offers proof-of-concept for a treatment approach to prevent breast cancer recurrence.

Jin Lab: How tumours trick the brain into shutting down cancer-fighting cells

Lung cancer in mice hijacks neurons to send a signal that subdues the immune system, study finds.

Chodosh Lab and Gade Lab: Research Grant Winners: Dr. Christine Edmonds and Dr. Lewis Chodosh of Penn Medicine